Instituto de Biologia Experimental e Tecnológica (iBET)

Address Av. República, Qta. do Marquês
Estação Agronómica Nacional
Edifício IBET/ITQB
Oeiras, Portugal
Platforms ATMP & Biological, Vaccines

iBET is a private not-for-profit research organization with over 30 years of experience in biopharmaceutical research. Our ambition is to overcome major challenges in bioprocess and bioengineering of biopharmaceuticals, namely in vaccines and ATMPs such as cell and gene therapy products. In addition, the development of new or improved analytical methods for vaccines and ATMPs, in agreement with good manufacturing practices (GMP) expands our research capabilities from process development to quality control and deep characterization of product attributes.

Our key areas of expertise include the development of bioprocesses and in-depth characterization methods for vaccines and Advanced Therapeutic Medicinal Products (ATMPs) such as viral vectors and stem cells for gene and cell therapy. In addition, iBET has proven expertise in the development of advanced 3D cell models for pre-clinical research and regenerative medicine. Our portfolio of advanced 3D cell models includes liver, central nervous system, cardiac tissue and cancer models. Noteworthy, the incorporation of immune cells into tumour models enables the development of 3D cell models for immuno-oncology research.

iBET is thus a unique research institute dedicated to the development of innovative solutions for the manufacturing of therapeutic products as a result from our specialized human resources and competences in cell culture, bioprocess development, downstream processing and in the development and validation of analytical assays. iBET has a long track record of partnerships with multinational biopharma companies, biotech companies, medical schools & hospitals. iBET has valuable experience in managing and participating in large research consortiums acquired with the coordination of more than 20 international projects and more than 100 work-packages in FP5, 6, 7 and H2020

By applying systems biology and comprehensive analytical tools, iBET performs genomic, transcriptomic, metabolomic, glycomic and proteomic (soluble and membrane-bound) analysis for detailed product characterization.

iBET’s Analytical Services Unit is certified for Good Manufacturing Practices (cGMP) for the analysis of both human and veterinary products. The privileged access to GenIbet Biopharmaceuticals enables completing the manufacturing process from ideation and development to production and release under cGMP conditions thus.