EATRIS’ contribution to research findings

A non-exhaustive list of publications citing EATRIS

EATRIS, the European Research Infrastructure for Translational Medicine and A_IATRIS, its Italian node

Authors: Moretti, F; Andreu, AL; Ussi, A; Minghetti, L;

Year: 2020

Journal: The International Journal of Biological Markers

DOI: 10.1177/1724600820902781

Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1-¹³ C]pyruvate

Authors: Nivajärvi, R; Olsson, V; Hyppönen, V; Bowen, S; Leinonen, HM; Lesch, HP; Ardenkjaer-Larsen, JH; Gröhn, OHJ; Ylä-Herttuala, S; Kettunen, MI;

Year: 2020

Journal: NMR in Biomedicine

DOI: 10.1002/nbm.4250

A Comparative Analysis of Multipotent Mesenchymal Stromal Cells derived from Different Sources, with a Focus on Neuroregenerative Potential

Authors: Petrenko, Y; Vackova, I; Kekulova, K; Chudickova, M; Koci, Z; Turnovcova, K; Kupcova Skalnikova, H; Vodicka, P; Kubinova, S;

Year: 2020

Journal: Scientific Reports, Nature Research

DOI: 10.1038/s41598-020-61167-z

Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors

Authors: Řehulka, J; Vychodilová, K; Krejčí, P; Gurská, S; Hradil, P; Hajdúch, M; Džubák, P; Hlaváč, J;

Year: 2020

Journal: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2020.112176

Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study

Authors: Leeksma, AC; Baliakas, P; Moysiadis, T; Puiggros, A; Plevova, K; van der Kevie-Kersemaekers, AM; Posthuma, H; Rodriguez-Vicente, AE; Tran, AN; Barbany, G; Mansouri, L; Gunnarsson, R; Parker, H; van den Berg, E; Bellido, M; Davis, Z; Wall, M; Scarpelli, I; Österborg, A; Hansson, L; Jarosova, M; Ghia, P; Poddighe, P; Espinet, B; Pospisilova, S; Tam, C; Ysebaert, L; Nguyen-Khac, F; Oscier, D;Haferlach, C; Schoumans, J; Stevens-Kroef, M; Eldering, E; Stamatopoulos, K; Rosenquist, R; Strefford, JC; Mellink, C; Kater, AP;

Year: 2020

Journal: Haematologica Journal of The Ferrata Storti Foundation

DOI: 10.3324/haematol.2019.239947

HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells

Authors: Arasu, UT; Deen, AJ; Pasonen-Seppänen, S; Heikkinen, S;Lalowski, M; Kärnä, R; Härkönen, K; Mäkinen, P; Lázaro-Ibáñez, E; Siljander, PR; Oikari, S; Levonen, AL; Rilla, K;

Year: 2019

Journal: Cellular and Molecular Life Sciences

DOI: 10.1007/s00018-019-03399-5

A New Sensitive Method for the Detection of Mycoplasmas Using Fluorescence Microscopy

Authors: Ligasová, A; Vydržalová, M; Buriánová, R; Brůčková, L; Večeřová, R; Janošťáková, A; Koberna, K;

Year: 2019

Journal: Cells

DOI: 10.3390/cells8121510

The Healing of Oxidative Injuries with Trehalose in UVB-Irradiated Rabbit Corneas

Authors: Cejka, C; Kossl, J; Hermankova, B; Holan, V; Kubinova, S; Olmiere, C; Cejkova, J;

Year: 2019

Journal: Oxidative Medicine and Cellular Longevity

DOI: 10.1155/2019/1857086

In vitro antileishmanial activity of leaf and stem extracts of seven Brazilian plant species

Authors: de Paula, RC;da Silva, SM;Faria, KF;Frézard, F;Moreira, CPS;Foubert, K;Lopes, JCD;Campana, PRV;Rocha, MP;Silva, AF;Silva, CG;Pieters, L;Almeida, VL;

Year: 2019

Journal: Journal of Ethnopharmacology

DOI: 10.1016/j.jep.2018.12.026

Metabolic Changes in Focal Brain Ischemia in Rats Treated With Human Induced Pluripotent Stem Cell-Derived Neural Precursors Confirm the Beneficial Effect of Transplanted Cells

Authors: Jirak, D; Ziolkowska, N; Turnovcova, K; Karova, K; Sykova, E; Jendelova, P; Romanyuk, N;

Year: 2019

Journal: Front Neurol

DOI: 10.3389/fneur.2019.01074

Clinical impact of genomic analysis in children with B-acute lymphoblastic leukemia: A pilot study in Slovakia

Authors: Vaska, A; Makohusova, M; Plevova, K; Skalicka, K; Cermak, M; Chovanec, F; Fabri, O; Svec, P; Kolenova, A;

Year: 2019

Journal: Neoplasma

DOI: 10.4149/neo_2019_190328N274

Soft and rigid scaffolds for spinal cord injury regeneration

Authors: Kubinova, Š;

Year: 2019

Journal: Spinal Cord Injury (SCI) Repair Strategies

DOI: 10.5210/jbc.v43i2.10331

Integrative Modeling and Visualization of Exosomes

Authors: Jimenez, J; Autin, L; De Cáceres, I; Goodsell, D;

Year: 2019

Journal: Journal of Biological Chemistry

DOI: 10.5210/jbc.v43i2.10331

Translatie als filosofisch programma–een verkenning

Authors: Glas, G;

Year: 2019

Journal: Algemeen Nederlands Tijdschrift voor Wijsbegeerte

DOI: 10.30950//jcer.v15i3.1028

Who Is ERIC? The Politics and Jurisprudence of a Governance Tool for Collaborative European Research Infrastructures

Authors: Moskovko, M; Ástvaldsson, A; Hallonsten, O;

Year: 2019

Journal: JCER

DOI: 10.30950//jcer.v15i3.1028

Quantification of Nitric Oxide and Reactive Oxygen Species in Leishmania-infected J774A.1 Macrophages as a Response to the in vitro Treatment with a Natural Product Compound

Authors: Karampetsou, K; Koutsoni, O; Dotsika, E;

Year: 2019

Journal: BIO-PROTOCOL

DOI: 10.21769/BioProtoc.3442

In vitro Screening of Antileishmanial Activity of Natural Product Compounds: Determination of IC50, CC50 and SI Values

Authors: Koutsoni, O;Karampetsou, K;Dotsika, E;

Year: 2019

Journal: BIO-PROTOCOL

DOI: 10.21769/BioProtoc.3410

EU law and policy on new health technologies

Authors: Brosset, E;Mahalatchimy, A;

Journal: Book

Sinogram Space activity estimation for the IAEA PGET detector

Authors: Presotto, L;

Year: 2019

Informed Consent in Translational/Clinical Research. Ethical Issues According to International Guidelines

Authors: Daverio, M;

Year: 2019

Journal: BioLaw Journal-Rivista di BioDiritto

Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy

Authors: Krafcikova, M;Dzatko, S;Caron, C;Granzhan, A;Fiala, R;Loja, T;Teulade-Fichou, MP;Fessl, T;Hänsel-Hertsch, R;Mergny, JL;Foldynova-Trantirkova, S;Trantirek, L;

Year: 2019

Journal: Journal of the American Chemical Society

DOI: 10.1021/jacs.9b03031

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs

Authors: Karttunen, J;Heiskanen, M;Navarro-Ferrandis, V;Das Gupta, S;Lipponen, A;Puhakka, N;Rilla, K;Koistinen, A;Pitkänen, A;

Year: 2019

Journal: Journal of Extracellular Vesicles

DOI: 10.1080/20013078.2018.1555410

Harnessing the untapped potential of nucleotide-binding oligomerization domain ligands for cancer immunotherapy

Authors: Nabergoj, S; Mlinarič-Raščan, I; Jakopin, Ž;

Year: 2019

Journal: Medical Research Reviews

DOI: 10.1002/med.21557

Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)

Authors: Melero-Fernandez de Mera, RM;Arasu, UT;Kärnä, R;Oikari, S;Rilla, K;Vigetti, D;Passi, A;Heldin, P;Tammi, MI;Deen, AJ;

Year: 2019

Journal: Matrix Biology

DOI: 10.1016/j.matbio.2018.10.004

Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells

Authors: Ahmad, JN; Holubova, J; Benada, O; Kofronova, O; Stehlik, L; Vasakova, M; Sebo, P;

Year: 2019

Journal: Microbe Biology

DOI: 10.1128/mBio.01743-19

Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase

Authors: Skrott, Z;Majera, D;Gursky, J;Buchtova, T;Hajduch, M;Mistrik, M;Bartek, J;

Year: 2019

Journal: Oncogene

DOI: 10.1038/s41388-019-0915-2

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX

Authors: Grüner, B;Brynda, J;Das, V;Šícha, V;Štěpánková, J;Nekvinda, J;Holub, J;Pospíšilová, K;Fábry, M;Pachl, P;Král, V;Kugler, M;Mašek, V;Medvedíková, M;Matějková, S;Nová, A;Lišková, B;Gurská, S;Džubák, P;Hajdúch, M;Řezáčová, P;

Year: 2019

Journal: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.9b00945

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

Authors: Härkönen, K; Oikari, S; Kyykallio, H; Capra, J; Hakkola, S; Ketola, K; Thanigai Arasu, U; Daaboul, G; Malloy, A; Oliveira, C; Jokelainen, O; Sironen, R; Hartikainen, JM; Rilla, K;

Year: 2019

Journal: Cells

DOI: 10.3390/cells8030276

Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

Authors: Bereshchenko, O;Lo Re, O;Nikulenkov, F;Flamini, S;Kotaskova, J;Mazza, T;Le Pannérer, MM;Buschbeck, M;Giallongo, C;Palumbo, G;Li Volti, G;Pazienza, V;Cervinek, L;Riccardi, C;Krejci, L;Pospisilova, S;Stewart, AF;Vinciguerra, M;

Year: 2019

Journal: Clinical Epigenetics

DOI: 10.1186/s13148-019-0724-z

Value of pre-operative CTX serum levels in the prediction of medication-related osteonecrosis of the jaw (MRONJ): a retrospective clinical study

Authors: Salgueiro, M; Stribos, M; Zhang, LF; Stevens, M; Awad, ME; Elsalanty, M;

Year: 2019

Journal: EPMA Journal

DOI: 10.1007/s13167-019-0160-3

Nano-formulated curcumin (Lipodisq™) modulates the local inflammatory response, reduces glial scar and preserves the white matter after spinal cord injury in rats

Authors: Krupa, P; Svobodova, B; Dubisova, J; Kubinova, S; Jendelova, P; Machova Urdzikova, L;

Year: 2019

Journal: Neuropharmacology

DOI: 10.1016/j.neuropharm.2019.05.018

Quantification of fixed adherent cells using a strong enhancer of the fluorescence of DNA dyes

Authors: Ligasová, A; Koberna, K;

Year: 2019

Journal: Sci Rep

DOI: 10.1038/s41598-019-45217-9

The effect of 808 nm and 905 nm wavelength light on recovery after spinal cord injury

Authors: Svobodova, B;Kloudova, A;Ruzicka, J;Kajtmanova, L;Navratil, L;Sedlacek, R;Suchy, T;Jhanwar-Uniyal, M;Jendelova, P;Machova Urdzikova, L;

Year: 2019

Journal: Scientific Reports

DOI: 10.1038/s41598-019-44141-2

Residues 529 to 549 participate in membrane penetration and pore-forming activity of the Bordetella adenylate cyclase toxin

Authors: Roderova, J;Osickova, A;Sukova, A;Mikusova, G;Fiser, R;Sebo, P;Osicka, R;Masin, J;

Year: 2019

Journal: Scientific Reports

DOI: 10.1038/s41598-019-42200-2

Hydrazones as novel epigenetic modulators: Correlation between TET 1 protein inhibition activity and their iron(II) binding ability

Authors: Jakubek, M;Kejík, Z;Kaplánek, R;Antonyová, V;Hromádka, R;Šandriková, V;Sýkora, D;Martásek, P;Král, V;

Year: 2019

Journal: Bioorganic Chemistry

DOI: 10.1016/j.bioorg.2019.02.034

Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target

Authors: Bříza, T;Králová, J;Rimpelová, S;Havlík, M;Kaplánek, R;Kejík, Z;Martásek, P;Mikula, I;Džubák, P;Hajdúch, M;Ruml, T;Král, V;

Year: 2019

Journal: Bioorganic Chemistry

DOI: 10.1016/j.bioorg.2018.02.011

Clinically Relevant Solution for the Hypothermic Storage and Transportation of Human Multipotent Mesenchymal Stromal Cells

Authors: Petrenko, Y; Chudickova, M; Vackova, I; Groh, T; Kosnarova, E; Cejkova, J; Turnovcova, K; Petrenko, A; Sykova, E; Kubinova, S;

Year: 2019

Journal: Stem Cells International

DOI: 10.1155/2019/5909524

Prooxidant activity of phenolic stabilizers in polyolefins during accelerated photooxidation

Authors: Šlouf, M; Michálková, D;Gajdošová, V; Dybal, J; Pilař, J;

Year: 2019

Journal: Polymer Degradation and Stability

DOI: 10.1016/j.polymdegradstab.2019.06.013

Strategy for improved therapeutic efficiency of curcumin in the treatment of gastric cancer

Authors: Jakubek, M; Kejík, Z; Kaplánek, R; Hromádka, R; Šandriková, V; Sýkora, D;Antonyová, V; Urban, M; Dytrych, P; Mikula, I; Martásek, P; Král, V;

Year: 2019

Journal: Biomedicine & Pharmacotherapy

DOI: 10.1016/j.biopha.2019.109278

Research activity and capability in the European reference network MetabERN

Authors: Heard, JM; Bellettato, C; van Lingen, C; Scarpa, M;, ;

Year: 2019

Journal: Orphanet Journal of Rare Diseases

DOI: 10.1186/s13023-019-1091-8

Clinical biomarker innovation: when is it worthwhile?

Authors: Kluytmans, A; Deinum, J; Jenniskens, K; van Herwaarden, AE; Gloerich, J; van Gool, AJ ;van der Wilt, GJ; Grutters, JPC;

Year: 2019

Journal: Clinical Chemistry and Laboratory Medicine (CCLM)

DOI: 10.1515/cclm-2019-0098

Public health and evidence-informed policy-making: The case of a commonly used herbicide

Author: Vainio, H;

Year: 2019

Journal: Scand J Work Environ Health

DOI: 10.4337/9781785364723.00020

Correlative light and electron microscopy is a powerful tool to study interactions of extracellular vesicles with recipient cells

Authors: Arasu, UT;Härkönen, K;Koistinen, A;Rilla, K;

Year: 2019

Journal: Experimental Cell Research

DOI: 10.1016/j.yexcr.2019.02.004

Building a Professional Identity and an Academic Career Track in Translational Medicine

Authors: van Dijk, SJ;Domenighetti, AA;Gomez-Ospina, N;Hunter, P;Lindemans, CA;Melotte, V;van Rossum, AMC;Rosenblum, ND;

Year: 2019

Journal: Frontiers in Medicine (Lausanne)

DOI: 10.3389/fmed.2019.00151

The future of protein biomarker research in type 2 diabetes mellitus

Authors: Tans, R; Verschuren, L; Wessels, HJCT; Bakker, SJL; Tack, CJ; Gloerich, J; van Gool, AJ;

Year: 2019

Journal: Expert Review Proteomics

DOI: 10.1080/14789450.2018.1551134

Fibroblast as a critical stromal cell type determining prognosis in prostate cancer

Authors: Blom, S; Erickson, A; Östman, A; Rannikko, A; Mirtti, T; Kallioniemi, O; Pellinen, T;

Year: 2019

Journal: The Prostate

DOI: 10.1002/pros.23867

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

Authors: Nowikow, C;Fuerst, R;Kauderer, M;Dank, C;Schmid, W;Hajduch, M;Rehulka, J;Gurska, S;Mokshyna, O;Polishchuk, P;Zupkó, I;Dzubak, P;Rinner, U;

Year: 2019

Journal: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2019.07.048

Detection of breast cancer lymph node metastases in frozen sections with a point-of-care low-cost microscope scanner

Authors: Holmström, O; Linder, N; Moilanen, H; Suutala, A; Nordling, S ; Ståhls, A; Lundin, M; Diwan, V; Lundin, J;

Year: 2019

Journal: PLoS ONE

DOI: 10.1371/journal.pone.0208366

Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety

Authors: Pomeisl, K; Krečmerová, M; Pohl, R; Snoeck, R; Andrei, G;

Year: 2019

Journal: Tetrahedron

DOI: 10.1016/j.tet.2019.130529

Synthetic Biology and the Translational Imperative

Authors: Heidari Feidt, R; Ienca, M; Elger, BS; Folcher, M;

Year: 2019

Journal: Science and Engineering Ethics

DOI: 10.1007/s11948-017-0011-3

Policies and actions to tackle rare diseases at European level

Authors: Montserrat, A; Taruscio, D;

Year: 2019

Annali Dell Istítuto Superiore di Sanita

DOI: 10.4415/ANN_19_03_17

“From lab bench to store shelves:” A translational research & development framework for linking university science and engineering research to commercial outcomes

Author: Bazan, C;

Year: 2019

Journal: Journal of Engineering and Technology Management

DOI: 10.1016/j.jengtecman.2019.05.001

Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells

Authors: Tanner, R; Smith, SG; van Meijgaarden, KE; Giannoni, F; Wilkie, M; Gabriele, L; Palma, C; Dockrell, HM; Ottenhoff, THM; McShane, H;

Year: 2019

Journal: Journal of Immunological Methods

DOI: 10.1016/j.jim.2019.01.006

Benzoisothiazole-1,1-dioxide-based synthetic receptor for zinc ion recognition in aqueous medium and its interaction with nucleic acids

Authors: Jakubek, M; Kejík, Z; Antonyová, V; Kaplánek, R; Sýkora, D;Hromádka, R; Vyhlídalová, K; Martásek, P; Král, V;

Year: 2019

Journal: Supramolecular Chemistry

DOI: 10.1080/10610278.2018.1523409

Financializing epistemic norms in contemporary biomedical innovation

Authors: Robinson, M;

Year: 2019

Journal: Synthese

DOI: 10.1007/s11229-018-1704-0

A genetic risk score predicts recurrent events after myocardial infarction in young adults

Authors: Rincón, LM;Sanmartín, M;Alonso, GL;Rodríguez, JA;Muriel, A;Casas, E;Navarro, M;Carbonell, A;Lázaro, C;Fernández, S;González, P;Rodríguez, M;Jiménez-Mena, M;Fernández-Golfín, C;Esteban, A;García-Bermejo, ML;Zamorano, JL;

Year: 2019

Journal: Revista Española de Cardiología (English Edition)

DOI: 10.1016/j.rec.2019.08.006

Achieving reproducibility and accuracy in cancer mutation detection with whole-genome and whole-exome sequencing

Author: Xiao, W;

Year: 2019

Journal: BioRxiv

DOI: 10.1101/626440

Establishing reference samples for detection of somatic mutations and germline variants with NGS technologies

Authors: Fang, LT;Zhu, B;Zhao, Y;Chen, W;Yang, Z;Kerrigan, L;

Year: 2019

Journal: BioRxiv

DOI: 10.1101/625624

The Fundamental Characteristics of a Translational Scientist

Authors: Gilliland, C; White, J;Gee, B; Kreeftmeijer-Vegter, R; Bietrix, F; Ussi, A; Hajduch, M; Kocis, P; Chiba, N;Hirasawa, R; Suematsu, M; Bryans, J; Newman, S; Hall, M; Austin, C;

Year: 2019

Journal: American Chemical Society

DOI: 10.1021/acsptsci.9b00022

Bridging the valley of death in biomedicine with translational research: Assessing the impact of National Institutes of Health’s Clinical and Translational Science Award

Author: Kim, Yeon Hak Hak

Year: 2019

Source: Dissertation

Monitoring DNA-Ligand Interactions in Living Human Cells Using High-Resolution NMR Spectroscopy

Authors: Krafcikova, M;Dzatko, S;Caron, C;Granzhan, A;Fiala, R;Loja, T;Teulade-Fichou, M;Fessl, T;Hansel-Hertsch, R;Mergny, J;Trantirek, L;Trantirek, L;

Year: 2019

Journal: chemRxiv

DOI: 10.26434/chemrxiv.8107772.v1

Towards Key Performance Indicators of Research Infrastructures

Authors: Kolar, J; Cugmas, M; Ferligoj, A;

Year: 2019

High speed of fork progression induces DNA replication stress and genomic instability

Authors: Maya-Mendoza, A; Moudry, P; Merchut-Maya, JM; Lee, M; Strauss, R; Bartek, J;

Year: 2018

Journal: Nature

DOI: 0.1038/s41586-018-0261-5

Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells

Authors: Dzatko, S; Krafcikova, M; Hänsel-Hertsch, R; Fessl, T; Fiala, R; Loja, T; Krafcik, D; Mergny, JL; Foldynova-Trantirkova, S; Trantirek, L;

Year: 2018

Journal: Angew. Chem. Int. Ed. Engl.

DOI: 10.1002/anie.201712284

P04.28 Effect of fibroblast activation protein-expressing stromal cells from human glioblastomas on glioma and endothelial cells

Authors: Busek, P; Balaziova, E; Mateu, R; Vymola, P; Vlasicova, K; Sedo, A;

Year: 2018

Journal: Neuro-Oncology

DOI: 10.1093/neuonc/noy139.262

Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status

Authors: Kubesova, B;Pavlova, S;Malcikova, J;Kabathova, J;Radova, L;Tom, N;Tichy, B;Plevova, K;Kantorova, B; Fiedorova, K;Slavikova, M;Bystry, V;Kissova, J;Gisslinger, B;Gisslinger, H;Penka, M;Mayer, J;Kralovics, R;Pospisilova, S;Doubek, M;

Year: 2018

Journal: Leukemia

DOI: 10.1038/leu.2017.230

Advancing food, nutrition, and health research in Europe by connecting and building research infrastructures in a DISH-RI: Results of the EuroDISH project

Authors: Snoek, H; Eijssen, L;Geurts, M;Vors, C;Brown, K;Bogaardt, M;Dhonukshe-Rutten, R;Evelo, C;Fezeu, L;Finglas, P;Laville, M;Ocké, M;Perozzi, G;Poppe, K;Slimani, N;Tetens, I;Timotijevic, L;Zimmermann, K;van ’t Veer, P;

Year: 2018

Journal: Trends in Food Science & Technology

DOI: 10.1016/j.tifs.2017.12.015

Differential but Complementary HIF1α and HIF2α Transcriptional Regulation

Authors: Downes, NL;Laham-Karam, N;Kaikkonen, MU;Ylä-Herttuala, S;

Year: 2018

Journal: Mol. Ther.

DOI: 10.1016/j.ymthe.2018.05.004

HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome

Authors: Belizna, C;Pregnolato, F;Abad, S;Alijotas-Reig, J;Amital, H;Amoura, Z;Andreoli, L;Andres, E;Aouba, A;Apras Bilgen, S;Arnaud, L;Bienvenu, B;Bitsadze, V;Blanco, P;Blank, M;Borghi, MO;Caligaro, A;Candrea, E;Canti, V;Chiche, L;Chretien, JM;Cohen Tervaert, JW;Damian, L;Delross, T;Dernis, E;Devreese, K;Djokovic, A;Esteve-Valverde, E;Favaro, M;Fassot, C;Ferrer-Oliveras, R;Godon, A;Hamidou, M;Hasan, M;Henrion, D;Imbert, B;Jeandel, PY;Jeannin, P;Jego, P;Jourde-Chiche, N;Khizroeva, J;Lambotte, O;Landron, C;Latino, JO;Lazaro, E;de Leeuw, K;Le Gallou, T;Kiliç, L;Limper, M;Loufrani, L;Lubin, R;Magy-Bertrand, N;Mahe, G;Makatsariya, A;Martin, T;Muchardt, C;Nagy, G;Omarjee, L;Van Paasen, P;Pernod, G;Perrinet, F;Pïres Rosa, G;Pistorius, MA;Ruffatti, A;Said, F;Saulnier, P;Sene, D;Sentilhes, L;Shovman, O;Sibilia, J;Sinescu, C;Stanisavljevic, N;Stojanovich, L;Tam, LS;Tincani, A;Tollis, F;Udry, S;Ungeheuer, MN;Versini, M;Cervera, R;Meroni, PL;

Year: 2018

Journal: Autoimmune Reviews

DOI: 10.1016/j.autrev.2018.05.012

Optical microchips based on high-affinity recombinant protein binders—Human serum albumin detection in urine

Authors: Semeradtova, A;Stofik, M;Vankova, L;Maly, P;Stanek, O;Maly, J;

Year: 2018

Journal: Sensors and Actuators B: Chemical

DOI: 10.1016/j.snb.2018.05.180

Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity

Authors: Burglová, K; Rylová, G; Markos, A; Prichystalova, H; Soural, M; Petracek, M; Medvedikova, M; Tejral, G; Sopko, B; Hradil, P; Dzubak, P; Hajduch, M; Hlavac, J;

Year: 2018

Journal: J. Med. Chem.

DOI: 10.1021/acs.jmedchem.8b00078

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence

Authors: Mrazkova, B;Dzijak, R;Imrichova, T;Kyjacova, L;Barath, P;Dzubak, P;Holub, D;Hajduch, M;Nahacka, Z;Andera, L; Holicek, P;Vasicova, P;Sapega, O;Bartek, J;Hodny, Z;

Year: 2018

Journal: Aging (Albany NY)

DOI: 10.18632/aging.101404

Biocompatible glyconanomaterials based on HPMA-copolymer for specific targeting of galectin-3

Authors: Bojarová, P; Tavares, MR; Laaf, D;Bumba, L; Petrásková, L; Konefał, R; Bláhová, M; Pelantová, H; Elling, L; Etrych, T; Chytil, P; Křen, V;

Year: 2018

Journal: J Nanobiotechnology

DOI: 10.1186/s12951-018-0399-1

Metallomics for Alzheimer\’s disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties

Authors: D’Acunto, CW;Kaplánek, R;Gbelcová, H;Kejík, Z;Bříza, T;Vasina, L;Havlík, M;Ruml, T;Král, V;

Year: 2018

Journal: Eur J Med Chem

DOI: 10.1016/j.ejmech.2018.02.084

Biobanks in Horizon 2020: sustainability and attractive perspectives

Authors: Kinkorová, J; Topolčan, O;

Year: 2018

Journal: EPMA J

DOI: 10.1007/s1316

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells

Authors: Odorico, J;Markmann, J;Melton, D;Greenstein, J;Hwa, A;Nostro, C;Rezania, A;Oberholzer, J;Pipeleers, D;Yang, L;Cowan, C;Huangfu, D;Egli, D;Ben-David, U;Vallier, L;Grey, ST;Tang, Q;Roep, B;Ricordi, C;Naji, A;Orlando, G;Anderson, DG;Poznansky, M;Ludwig, B;Tomei, A;Greiner, DL;Graham, M;Carpenter, M;Migliaccio, G;D’Amour, K;Hering, B;Piemonti, L;Berney, T;Rickels, M;Kay, T;Adams, A;

Year: 2018

Journal: Transplantation

DOI: 10.1097/TP.0000000000002217

Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling

Authors: Bumba, L; Laaf, D; Spiwok, V; Elling, L; Křen, V; Bojarová, P;

Year: 2018

Journal: International Journal of Molecular Sciences

DOI: 10.3390/ijms19020372

Identification of microRNAs differentially expressed in glioblastoma stem-like cells and their association with patient survival

Authors: Sana, J;Busek, P;Fadrus, P;Besse, A;Radova, L;Vecera, M;Reguli, S;Stollinova Sromova, L;Hilser, M;Lipina, R;Lakomy, R;Kren, L;Smrcka, M;Sedo, A;Slaby, O;

Year: 2018

Journal: Scientific Reports

DOI: 10.1038/s41598-018-20929-6

Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM

Authors: Pokorny, J; Krajcovicova, S; Hajduch, M; Holoubek, M; Gurska, S; Dzubak, P; Volna, T; Popa, I; Urban, M;

Year: 2018

Journal: Future Med Chem

DOI:10.4155/fmc-2017-0171

Feasibility of PET/CT system performance harmonisation for quantitative multicentre 89Zr studies

Authors: Kaalep, A; Huisman, M; Sera, T; Vugts, D; Boellaard,

Year: 2018

Journal: EJNMMI Physics

DOI: 10.1186/s40658-018-0226-7

Innovation Partnership for a Roadmap on Vaccines in Europe (IPROVE): A vision for the vaccines of tomorrow

Authors: Medaglini, D;De Azero, MR;Leroy, O;Bietrix, F;Denoel, P;

Year: 2018

Journal: Vaccine

DOI: 10.1016/j.vaccine.2017.11.069

Cardiac amyloidosis: from clinical suspicion to morphological diagnosis

Authors: Flodrova, P;Flodr, P;Pika, T;Vymetal, J;Holub, D;Dzubak, P;Hajduch, M;Scudla, V;

Year: 2018

Journal: Pathology

DOI: 10.1016/j.pathol.2017.10.012

Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers

Authors: Hasan, S; Kulkarni, NN; Asbjarnarson, A; Linhartova, I; Osicka, R; Sebo, P; Gudmundsson, GH;

Year: 2018

Journal: Infection and Immunity

DOI: 10.1128/IAI.00445-17

Protein biomarkers for subtyping breast cancer and implications for future research

Authors: Mueller, C; Haymond, A; Davis, JB; Williams, A; Espina, V;

Year: 2018

Journal: Expert Review of Proteomics

DOI: 10.1080/14789450.2018.1421071

Academia-industry Cooperation in the Medical Field: Matching Opportunities in Japan

Authors: Tsuruya, N; Kawashima, T; Shiozuka, M; Nakanishi, Y; Sugiyama, D;

Year: 2018

Journal: Clinical Therapeutics

DOI: 10.1016/j.clinthera.2018.10.010

The Current State of Advanced Therapy Medicinal Products in the Czech Republic

Authors: Kočí, Z; Boráň, T; Krůpa, P; Kubinová, Š;

Year: 2018

Journal: Human Gene Therapy Clinical Development

DOI: 10.1089/humc.2018.035

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice

Authors: Merentie, M;Rissanen, R;Lottonen-Raikaslehto, L;Huusko, J;Gurzeler, E;Turunen, MP;Holappa, L;Mäkinen, P;Ylä-Herttuala, S;

Year: 2018

Journal: PLoS ONE

DOI: 10.1371/journal.pone.0190981

The Nordic EMBL Partnership – a paragon of collaboration

Author: Ruffell, D;

Year: 2018

Journal: FEBS Letters

Silica-based nanoparticles are efficient delivery systems for temoporfin

Authors: Brezániová, I;Záruba, K;Králová, J;Sinica, A;Adámková, H;Ulbrich, P;Poučková, P;Hrubý, M;Štěpánek, P;Král, V;

Year: 2018

Journal: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2017.12.014

ToTem: a tool for variant calling pipeline optimization

Authors: Tom, N;Tom, O;Malcikova, J;Pavlova, S;Kubesova, B;Rausch, T;Kolarik, M;Benes, V;Bystry, V;Pospisilova, S;

Year: 2018

Journal: BMC Bioinformatics

DOI: 10.1186/s12859-018-2227-x

Healthy bi-regional connection: The EU-LAC Health initiative has promoted equitable and collaborative health research and innovation

Authors: Corral, T; de Román, M; Gómez-Núñez, AJ; Mourenza, B; Quental, C; Splett-Rudolf, S; de Andrés, R;

Year: 2018

Journal: Health Research Policy and Systems

DOI: 10.1186/s12961-018-0390-1

Towards a sustainable EU health information system infrastructure: A consensus driven approach

Authors: Bogaert, P; van Oers, H; Van Oyen, H;

Year: 2018

Journal: Health Policy

DOI: 10.1016/j.healthpol.2018.10.009

A checklist for clinical trials in rare disease: obstacles and anticipatory actions-lessons learned from the FOR-DMD trial

Authors: Crow, RA;Hart, KA;McDermott, MP;Tawil, R;Martens, WB;Herr, BE;McColl, E;Wilkinson, J;Kirschner, J;King, WM;Eagle, M;Brown, MW;Hirtz, D;Lochmuller, H;Straub, V;Ciafaloni, E;Shieh, PB;Spinty, S;Childs, AM;Manzur, AY;Morandi, L;Butterfield, RJ;Horrocks, I;Roper, H;Flanigan, KM;Kuntz, NL;Mah, JK;Morrison, L;Darras, BT;von der Hagen, M;Schara, U;Wilichowski, E;Mongini, T;McDonald, CM;Vita, G;Barohn, RJ;Finkel, RS;Wicklund, M;McMillan, HJ;Hughes, I;Pegoraro, E;Bryan Burnette, W;Howard, JF;Thangarajh, M;Campbell, C;Griggs, RC;Bushby, K;Guglieri, M;

Year: 2018

Journal: Trials

DOI: 10.1186/s13063-018-2645-0

Bordetella pertussis and Bordetella bronchiseptica filamentous hemagglutinins are processed at different sites

Authors: Jurnecka, D;Man, P; Sebo, P; Bumba, L;

Year: 2018

Journal: FEBS Open Bio

DOI: 10.1002/2211-5463.12474

Perimidine-based synthetic receptors for determination of copper(II) in water solution

Authors: Jakubek, M; Kejík, Z; Kaplánek, R; Veselá, H; Sýkora, D;Martásek, P; Král, V;

Year: 2018
Journal: Supramolecular Chemistry

DOI: 10.1080/10610278.2017.1414216

Translational research in the science policy debate: a comparative analysis of documents

Author: Blümel, C;

Year: 2018

Journal: Science and Public Policy

DOI: 10.1093/scipol/scx034

Optimising SME Potential in Modern Healthcare Systems: Challenges, Opportunities and Policy Recommendations

Authors: Horgan, D;van Kranen, HJ;Morré, SA;

Year: 2018

Journal: Public Health Genomics

DOI: 10.1159/000492809

Quantitative imaging, dosimetry and metrology; Where do National Metrology Institutes fit in?

Authors: Fenwick, AJ;Wevrett, JL;Ferreira, KM;Denis-Bacelar, AM;Robinson, AP;

Year: 2018

Journal: Applied Radiation and Isotopes

DOI: 10.1016/j.apradiso.2017.11.014

Rethinking biomedicine in the age of translational research: Organisational, professional, and epistemic encounters

Author: Crabu, S;

Year: 2018

Journal: Sociology Compass

DOI: 10.1111/soc4.12623

Comparison of Real-time Quantitative Polymerase Chain Reaction and Eight-color Flow Cytometry in Assessment of Minimal Residual Disease in Adult Acute Lymphoblastic Leukemia

Authors: Hrabovsky, S;Folber, F;Horacek, JM;Stehlikova, O;Jelinkova, H;Salek, C;Doubek, M;, ;

Year: 2018

Journal: Clinical Lymphoma Myeloma and Leukemia

DOI: 10.1016/j.clml.2018.06.030

Rational Drug Design Using Integrative Structural Biology

Authors: Chegkazi, MS;Mamais, M;Sotiropoulou, AI;Chrysina, ED;

Year: 2018

Journal: Methods in Molecular Biology

DOI: 10.1007/978-1-4939-8630-9_6

International Research Infrastructures-New research opportunities for biochemists and molecular biologists

Author: Stechmann, B;

Year: 2018

Journal: The FASEB Journal

Nuclear Medicine in Oncology

Authors: Oliveira, C; Parafita, R; Canudo, A; Castanheira, J; Costa, D;

Year: 2018

Journal: Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization

DOI: 10.1080/21681163.2016.1254068

Abstract 2805: Combretastatins as highly cytotoxic natural compounds

Authors: Dzubak, P; Rehulka, J; Gurska, S; Riener, U; Hajduch, M;

Year: 2018

Journal: Experimental and Molecular Therapeutics

DOI: 10.1158/1538-7445.AM2018-2805

Abstract 2643: Increased copy number ofEGFRgene is an independent outcome predictor in resected non-small cell lung cancer patients treated by adjuvant chemotherapy

Authors: Koudelakova, V; Trojanec, R; Potockova, J; Drabek, J; Stranska, J; Smickova, P; Kourilova, P; Grygarkova, I; Kolek, V; Skarda, J; Hajduch, M;

Year: 2018

Journal: Clinical Research (Excluding Clinical Trials)

DOI: 10.1158/1538-7445.AM2018-2643

Editorial to “Use of non-human primate disease models”

Authors: Vermeire, T; Badin, R; Langermans, J; Prescott, M;

Year: 2018
Journal: Drug Discovery Today: Disease Models

DOI: 10.1016/j.ddmod.2018.03.002

Governance design for RI platform for consumer behaviour and lifestyle: deliverable D13. 3

Authors: Bogaardt, MJ;Poppe, KJ;Selnes, T;Zimmermann, KL;

Year: 2018

Source: Conference

Sulle tracce degli interferoni: una vita nella ricerca

Author: Belardelli, F;

Year: 2018

Source: Dissertation

Bridging the translational innovation gap through good biomarker practice

Authors: van Gool, AJ; Bietrix, F; Caldenhoven, E; Zatloukal, K; Scherer, A; Litton, JE; Meijer, G; Blomberg, N; Smith, A; Mons, B; Heringa, J; Koot, WJ; Smit, MJ; Hajduch, M; Rijnders, T; Ussi, A;

Year: 2017

Journal: Nature Reviews Drug Discovery

DOI: 10.1038/nrd.2017.72

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up

Authors: Hartikainen, J;Hassinen, I;Hedman, A;Kivelä, A;Saraste, A;Knuuti, J;Husso, M;Mussalo, H;Hedman, M;Rissanen, TT;Toivanen, P;Heikura, T;Witztum, JL;Tsimikas, S;Ylä-Herttuala, S;

Year: 2017

Journal: European Heart Journal

DOI: 10.1093/eurheartj/ehx352

Matched preclinical designs for improved translatability

Authors: Aittokallio, T;Scherer, A;Poutanen, M;Freedman, LP;

Year: 2017

Journal: Science Translational Medicine

DOI: 10.1126/scitranslmed.aal4101

Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif

Authors: Wald, T;Spoutil, F;Osickova, A;Prochazkova, M;Benada, O;Kasparek, P;Bumba, L;Klein, OD;Sedlacek, R;Sebo, P;Prochazka, J;Osicka, R;

Year: 2017

Journal: Proceedings of the National Academy of Sciences U.S.A.

DOI: 10.1073/pnas.1615334114

Concepts and procedures for mapping food and health research infrastructure: New insights from the EuroDISH project

Authors: Brown, K;Timotijević, L;Geurts, M;Arentoft, J;Dhonukshe-Rutten, R;Fezeu, L;Finglas, P;Laville, M;Perozzi, G;Ocké, M;Poppe, K;Slimani, N;Snoek, H;Tetens, I;van’t Veer, P;Vors, C;Zimmermann, K;

Year: 2017

Journal: Trends in Food Science & Technology

DOI: 10.1016/j.tifs.2017.03.006

Structural features of subtype-selective EP receptor modulators

Authors: Markovič, T;Jakopin, Ž;Dolenc, MS;Mlinarič-Raščan, I;

Year: 2017

Journal: Drug Discovery Today

DOI: 10.1016/j.drudis.2016.08.003

Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein

Authors: Dvořáková, P;Bušek, P;Knedlík, T;Schimer, J;Etrych, T;Kostka, L;Stollinová Šromová, L;Šubr, V;Šácha, P;Šedo, A;Konvalinka, J;

Year: 2017

Journal: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.7b00767

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides

Authors: Tichý, M;Smoleń, S;Tloušt’ová, E;Pohl, R;Oždian, T;Hejtmánková, K;Lišková, B;Gurská, S;Džubák, P;Hajdúch, M;Hocek, M;

Year: 2017

Journal: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6b01766

Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal-Free Conditions

Authors: Lukovic, D;Diez Lloret, A;Stojkovic, P;Rodríguez-Martínez, D;Perez Arago, MA;Rodriguez-Jimenez, FJ;González-Rodríguez, P;López-Barneo, J;Sykova, E;Jendelova, P;Kostic, J;Moreno-Manzano, V;Stojkovic, M;Bhattacharya, SS;Erceg, S;

Year: 2017

Journal: Stem Cells Translational Medicine

DOI: 10.1002/sctm.16-0371

Addressing Pressing Needs in the Development of Advanced Therapies

Authors: Morrow, D;Ussi, A;Migliaccio, G;

Year: 2017

Journal: Frontiers in Bioengineering and Biotechnology

DOI: 10.3389/fbioe.2017.00055

Assessing opportunities for coordinated R&D in early cancer detection and management in Europe

Authors: Ussi, AE;Rebolj, M;Thorat, MA;Bietrix, F;Fauvel, AC;Hajdúch, M;Hill, C;Walker, I;van Engeland, M;Cuzick, J;Meijer, G;

Year: 2017

Journal: International Journal of Cancer

DOI: 10.1002/ijc.30564,

Glycan-decorated HPMA copolymers as high-affinity lectin ligands

Authors: Bojarová, P;Chytil, P;Mikulová, B;Bumba, L;Konefał, R;Pelantová, H;Krejzová, J;Slámová, K;Petrásková, L;Kotrchová, L;Cvačka, J;Etrych, T;Křen, V;

Year: 2017

Journal: Polymer Chemistry

DOI: 10.1039/C7PY00271H

cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity