Germans Trias i Pujol Research Institute (IGTP)

Address Camí de les Escoles s/n
08916 Badalona
Barcelona, Spain
Platforms Biomarkers, Imaging & Tracing

Brief description

The Germans Trias i Pujol Research Institute (IGTP) is a public research centre within the Can Ruti Campus for Biomedical Research, in Badalona (Barcelona). IGTP’s mission is to create a multi‐disciplinary and multi‐institutional environment that opens the gates to highly efficient translational research with a view to improving people’s health and quality of life.

 

The Institute, founded in 1995, is attached to one of the large teaching hospitals in the Barcelona area, the Germans Trias University Hospital. It is accredited as a Centre of Excellence of Catalonia under de CERCA and supervised by the Catalonian Government. Also, the IGTP is accredited as a Centre of Excellence by the Instituto Carlos III (Spanish Government) and in this capacity acts as an umbrella organization for scientific research on the campus, where it works closely with the other research institutions and the Germans Trias University Hospital, a situation that makes our campus an ideal focal point for synergies and attraction of talent.

More than 3,500 health professionals work in the Campus and over 700 are dedicated to research. Scientists work in 9 different areas of interest and publish an average of over 700 papers a year, contribute to improved treatment and healthcare protocols, produce patents and set up spin-off companies in order to improve the lives of patients. Besides, state of the art technological platforms including the new Centre of Comparative Medicine and Bioimage (CMCiB) provides a unique environment for cutting edge biomedical research.

Contact

Facility Translational Genomics Facility
Head of the facility
  • Maria del Pilar Armengol Barnils

Expertise

Technologies
  • SangerSequencing
  • NGS-Whole genome sequencing (WGS)
  • NGS-Exome sequencing(WES)
  • NGS-other
  • Multiplex ligation-dependent probe amplification (MLPA)
  • Genotyping
  • qPCR
  • Droplet Digital PCR (ddPCR)
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Infection medicine
  • Microbial Genomics
  • Single cells studies

Features

Certifications
  • ISO 9001:2008

Track record

Key opinion leaders
  • Miguel Angel Peinado
  • Roger Paredes

Contact

Facility High Content Genomics and Bioinformatics/Translational Genomics Facility
Head of the facility
  • Lauro Sumoy
  • Maria del Pilar Armengol

Expertise

Technologies
  • RT-PCR
  • NGS- RNA sequencing
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Human and pathogen transcriptomes
  • Non coding RNA analysis (miRNA, lncRNA, sRNA..)
  • Single cells studies

Features

Collaboration with industry where the institute collaborated with Transcriptomics expertise (in the last 5 years) <10
% of TIME involved in technology/methods development/innovation/intellectual property related to Transcriptomics 1

Contact

Facility High Content Genomics and Bioinformatics
Head of the facility
  • Lauro Sumoy

Expertise

Technologies
  • DNA Methylation Analysis – DNA methylation arrays
Purposes
  • Research
Applications
  • Biomarkers discovery and development
  • Disease processes research

Contact

Head of the facility
  • Jose Maria Hernandez Perez

Expertise

Technologies
  • Isoelectric focusing (IEF)
  • ELISA
  • Luminex
  • MALDI-MS
  • LC-MS
  • Liquid chromatography (HPLC, UHPLC)
  • MALDI TOF/TOF (autoflex speed BRUKER)
  • nano HPLC- nano ESIQQTOF (microtof BRUKER) and uPLC Agilent LC/MS/MS Agilent
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Expression proteomics
  • Interaction proteomics and protein networks
  • Post-translational modifications
  • Therapeutic development

Track record

Key opinion leaders
  • Josep Maria Estanyol
  • Francesc Canals
  • Eduard Salido
  • Pol Herrero
  • Eliandre de Oliveira
  • Carolina de la Torre
Publications

Contact

Head of the facility
  • Jose Maria Hernandez Perez

Expertise

Technologies
  • High performance liquid chromatography (HPLC,UHPLC)
  • MALDI-MS
  • LC-MS
  • Untargeted metabolomics assays
  • Targeted metabolomic assays
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research

Track record

Key opinion leaders
  • Pol Herrero (biomarkers and targeted metabolomics assays)
  • Antoni del Pino (biomarkers and targeted metabolomics assays)
Publications

DATA ANALYSIS for

  • Genomics
  • Proteomics
  • Metabolomics
  • Omics data integration / systems biology

DATA MANAGEMENT for

  • data backups
  • submission to databases (NCBI, GEO, SRA, ERA)

 

STATISTICS

  • Expertise in clinical design of experiments, clinical statistics
  • Informatics methods to support clinical decisions (diagnostic, predictive tests)
  • Molecular profiling (omics and others)
  • Metadata (patient/sample information)

BIOINFORMATICS

  • Gene annotation
  • Expression profiling with omics, microarrays, others (e.g. PCR) for RNAseq, microRNA, other RNA species
  • Methylation profiling with array-types
  • Data integration (“Systems biology”)
  • Genetic analysis for Structural variation detection (Genome, Exome) and prediction of protein function from sequence information

OMICS INTEGRATION METHODS

  • Published tools – Cytoscape, GSEA