MAQC Society’s 2022 SEQC2 Webinar Series – Hidden biases in germline structural variant detection

The MAQC Society is pleased to announce a new series of SEQC2 (Sequencing and Quality Control Phase 2) Webinars addressing the many challenges of analysis of massive datasets that come from Next-Gen Sequencing (NGS).  This year, in 2022, MAQC offers a new webinar series on diverse topics related to NGS:  copy-number pathogenicity, structural variation detection, use of internal standards and synthetic controls for variant detection, formalin-fixation impacts, and general reproducibility challenges.

On 3 May the webinar is titled: “Hidden biases in germline structural variant detection “ by Dr Fritz Sedlazeck Ph. D., Associate Professor, Human Genome Sequencing Center at Baylor College of Medicine. Dr Fritz Sedlazeck Ph. D. completed his PhD in 2012 in the group of Dr. Arndt von Haeseler at the Max F. Perutz Laboratory in Vienna. After a two year postdoc, he transitioned to the lab of Dr. Michael Schatz at Cold Spring Harbor Laboratory and later to Johns Hopkins University. Since 2017 he leads his own group at the Human Genome Sequencing Centre at Baylor College of Medicine. Dr. Sedlazeck groups focuses on the mechanisms of the formation of SV across multiple species and to improve our understanding how these complex alleles evolve and impact phenotypes.

Check out the other 5 webinars as well:

• 22. March 2022  – Zhichao Liu X-CNV: genome-wide prediction of the pathogenicity of copy number variations (LINK)
• 29 March 2022 – Yongmei Zhao Exploring best practices for structural variation detection in a cancer reference sample with multiple NGS platforms (LINK)
• 5 April 2022 – James C. Willey Advancing quality-control for NGS measurement of actionable mutations in circulating tumour DNA (LINK)
• 12 April 2022 – Joshua Xu Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples (LINK)
• 19 April 2022 – Tim R. Mercer Resolving the complexity of the human genome using synthetic chromosomal controls & Building a synthetic genome that encodes DNA, mRNA and protein controls (LINK)
• 3 May 2022 – Fritz Sedlazeck Hidden biases in germline structural variant detection

Read more here. Free registration for the webinars is open here.