Vall d’Hebron Institute of Research (VHIR)

Address Passeig Vall d’Hebron, 119 - 129
08035 Barcelona
Spain
Platforms ATMP & Biological, Biomarkers, Imaging & Tracing, Small Molecules

VHIR is a public sector institution that promotes and develops the biomedical research, innovation and teaching at Vall d’Hebron University Hospital (HUVH), the hospital of Barcelona and the largest of the Catalan Institute of Health (ICS).

Since its creation in 1994, VHIR works to find solutions to the health problems of society, and contribute to spread them around the world. In more than 20 years it has achieved leadership in biomedical research at hospitals in Spain, and aims to be recognised in 2020 as an excellent and competitive European Institute leader in clinical and translational research linked to a university hospital.

More than 1,300 people are working in the Institute, of which over 1,200 do research and others, and around 100 help to do it or transfer it to the society once made, whether in the form of projects, technology transfer and innovation, communication or fundraising, among others.

VHIR’s task is not only basic or translational; the Institute is leader in clinical research. It has the beds of the hospital separated in less than 50 meters of laboratories, and their patients will benefit from its research. This is understood by industry leaders who are committed to the hospital, making it a world reference for its first clinical trials.

Contact

Facility Rosa M Prieto

Expertise

Technologies
  • Genotyping
  • qPCR
Purposes
  • Research
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Epidemiology
  • Infection medicine
  • Microbial Genomics
  • Therapeutic development

Features

Collaboration with industry where the institute collaborated with Genomics expertise (in the last 5 years) >10
Certifications
  • ISO 9001: 2015

Track record

Key opinion leaders
  • Eduardo Tizzano, Head of the Clinical and Molecular Genetics group at VHIR
  • Marta Ribasés, Researcher of the Psychiatry, Mental Health and Addictions group at VHIR
  • Joan Montaner, Head of the Neurovascular Research group at VHIR
  • Ramon Martí, Head of the Neuromuscular and Mitochondrial Pathology group at VHIR.
  • Miguel Chillón, Head of the Gene Therapy of the Nervous System research group at VHIR
Publications

Contact

Head of the facility
  • Rosa M Prieto

Expertise

Technologies
  • RT-PCR
  • Microarrays
Purposes
  • Research
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Human and pathogen transcriptomes
  • Non coding RNA analysis (miRNA, lncRNA, sRNA..)
  • Responses to environment
  • Therapeutic development

Features

Collaboration with industry where the institute collaborated with Transcriptomics expertise (in the last 5 years) <10
Certifications
  • ISO 9001: 2015

Track record

Key opinion leaders
  • Sara Marsal Researcher of the Immunomediated Diseases and Innovative Therapies Group at VHIR
  • Eduardo Tizzano Head of the Medicine Genetics group at VHIR
  • Ivon Cuscó Researcher of the Medicine Genetics group at VHIR
  • Joan Montaner , Researcher of the Vascular Biology and Metabolism (VAM) group at VHIR
  • Marta Ribasés, Researcher of the Psychiatry, Mental Health and Addictions group at VHIR
Publications

Contact

Head of the facility
  • Rosa M Prieto

Expertise

Technologies
  • High performance liquid chromatography (HPLC,UHPLC)
  • LC-MS
  • Targeted metabolomic assays
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Responses to environment
  • Therapeutic development

Features

Collaboration with industry where the institute collaborated with Metabolomics expertise (in the last 5 years) <10
Certifications
  • ISO 9001: 2015

Track record

Key opinion leaders
  • Manuel Comabella, Head of the Neurology / Neuroimmunology Department at VHIR
  • Eva Colas, Research of the Medical Oncology Department at VHIR
Publications

DATA ANALYSIS for

  • Genomics
  • Proteomics
  • Metabolomics
  • Omics data integration / systems biology

DATA INTERPRETATION for

  • Genomics
  • Proteomics
  • Metabolomics
  • Omics data integration / systems biology

DATA MANAGEMENT for

  • FAIR data

DATA SUBMISSION in to public database

STATISTICS

  • Molecular profiling (omics and others)
  • Expertise in clinical design of experiments, clinical statistics
  • Metadata (patient/sample information)
  • Methods and policies for information infrastructure, including privacy and security

BIOINFORMATICS

  • Expression profiling with omics, microarray and others (e.g. PCR) for RNAseq, microRNA, other RNA species, proteins and metabolites
  • Methylation profiling with NGS and array-types
  • Data integration (“Systems biology”)
  • Genetic analysis for Structural variation detection (Genome, Exome)
  • Semantic analysis (“Bibliome analysis”, text mining)
  • Development of new algorithms, e.g. new decision algorithms, new sequence aligners for NGS data, etc.
  • Informatics methods to support clinical decisions (diagnostic, predictive tests)

OMICS INTEGRATION METHODS

  • Published tools – MixOmics