University Medical Center Utrecht (UMCU)

Address Heidelberglaan 100
3584 CX Utrecht
The Netherlands
Platforms Biomarkers, Imaging & Tracing

Laboratory of Translational Immunology

Innovative immunomonitoring

We offer  a immunomonitoring platform for research, pre-clinical and clinical studies which includes cellular phenotyping, functional assays, circulating and secreted biomarker discovery assays, HLA typing and  generic diagnostic. We are expert in harmonizing immunomonitoring protocols to reduce variations introduced by differences in logistics from sampling to analyses of the samples.

Contact

Head of the facility
  • Prof. dr. W. van Solinge

Expertise

Technologies
  • Luminex
  • MesoScale Discovery(MSD)
  • LC-MS
  • Protein chips
  • OLINK
Purposes
  • Research
  • Clinical use
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research

Features

Collaboration with industry where the institute collaborated with Proteomics expertise (in the last 5 years) >10
Certifications
  • ISO15189
  • ISO 9001

Track record

Key opinion leaders
  • Stefan Nierkens: translation of exploratory proteomice analyses to clinical implementation
  • Eveline Delemarre: data analyses
Publications

DATA ANALYSIS for

  • Proteomics
  • Metabolomics
  • Omics data integration / systems biology

 

DATA INTERPRETATION for

  • Proteomics
  • Metabolomics
  • Omics data integration / systems biology

 

DATA MANAGEMENT for

  • FAIR data

 

STATISTICS

  • SPSS; nonmem
  • Molecular profiling (omics and others)
  • Expertise in clinical design of experiments, clinical statistics
  • Metadata (patient/sample information)
  • Methods and policies for information infrastructure, including privacy and security

 

BIOINFORMATICS

  • Data integration (“Systems biology”)
  • Development of new algorithms, e.g. new decision algorithms, new sequence aligners for NGS data, etc.
  • Informatics methods to support clinical decisions (diagnostic, predictive tests)

 

OMICS INTEGRATION METHODS

  • Published tools
  • Own scripts/software

Contact

Facility ARCADIA
Head of the facility
  • Imo Hoefer, MD, PhD, FESC

Expertise

Technologies
  • NGS-Whole genome sequencing (WGS)
  • NGS-Exome sequencing(WES)
  • Genotyping
  • qPCR
Purposes
  • Research
  • Clinical use
Applications
  • Diagnostics and personalised disease profiling
  • Epidemiology

Features

Collaboration with industry where the institute collaborated with Genomics expertise (in the last 5 years) <10
Certifications
  • ISO 9001

Expertise

Technologies
  • RT-PCR
  • Microarrays
  • NGS- RNA sequencing
Purposes
  • Research
Applications
  • Biomarkers discovery and development
  • Single cells studies

Features

Certifications
  • ISO 9001

Get in touch

Emanuela Oldoni

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