Maimonides Biomedical Research Institute of Cordoba

Address Edificio IMIBIC, Hospital Universitario Reina Sofía,
Av. Menéndez Pidal, s/n, 14004
Córdoba, Spain
Platforms ATMP & Biological, Biomarkers

The Maimonides Biomedical Research Institute of Cordoba – IMIBIC, is a joint Institute of the University of Cordoba (UCO), the Reina Sofia University Hospital, and the Junta de Andalucía Regional government, created in 2008. It is structured in research groups commissioned by these institutions that cooperate in the implementation of the five scientific programmes, including Active aging and Fragility; Nutrition and endocrine and metabolic diseases; Infectious and immunological diseases and organ transplants; Cancer (Oncology and Oncohematology); and Chronic and Inflammatory Diseases.

IMIBIC brings together scientific research and medical practice to embrace integral projects with the ultimate aim to promote a much faster and efficient communication between clinical and preclinical research, and to generate knowledge of high impact with considerable potential of translation into practice, new therapies and innovative products.

One of the key activities at IMIBIC, and central for all its research programmes, is the identification, validation and development of biomarkers for the prevention, diagnosis and prognostic assessment of disease as well as for the prediction of therapy response.  IMIBIC offers a wide range of biomarker technologies, namely state of the art Bioinformatics, Genomics, Proteomics, Lipidomics, and Flow cytometry and Imaging technologies. In addition, it offers services for the production of mesenchyme cells, and a series of pre-clinical, clinical development and target validation services. Clinical findings can be easily redirected into preclinical experimentation within the Animal Experimentation Unit.

IMIBIC is accredited within the framework of health research centres of excellence recognised by the National Institute of Health Carlos III.

Institutes' Omics Technologies

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Contact

Head of the facility
  • Álvaro Jiménez Arranz

Expertise

Technologies
  • NGS-Exome sequencing(WES)
  • NGS-other
  • Genotyping
  • qPCR
  • Droplet Digital PCR (ddPCR)
  • NCounter FLEX (Nanostring Tech.)
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Microbial Genomics

Features

Collaboration with industry where the institute collaborated with Genomics expertise (in the last 5 years) <10
% of TIME involved in technology/methods development/innovation/intellectual property related to Genomics 10%

Track record

Key opinion leaders
  • Álvaro Jiménez-Arranz, NGS, Nanostring Technologies, ddPCR, qPCR, Clinical Genomics & Genetics
Publications

Contact

Head of the facility
  • Álvaro Jiménez Arranz

Expertise

Technologies
  • RT-PCR
  • NGS- RNA sequencing
  • NCounter FLEX (Nanostring Tech.)
Purposes
  • Research
  • Clinical use
  • Service
Applications
  • Biomarkers discovery and development
  • Diagnostics and personalised disease profiling
  • Disease processes research
  • Non coding RNA analysis (miRNA, lncRNA, sRNA..)

Features

Collaboration with industry where the institute collaborated with Transcriptomics expertise (in the last 5 years) <10
% of TIME involved in technology/methods development/innovation/intellectual property related to Transcriptomics 10%

Track record

Key opinion leaders
  • Álvaro Jiménez-Arranz, NGS, Nanostring Technologies, RT-PCR
Publications

Contact

Head of the facility
  • Eduardo Chicano-Galvez

Expertise

Technologies
  • MALDI-MS
  • LC-MS
  • Maldi Imaging / MS-Imaging
Purposes
  • Research
Applications
  • Biomarkers discovery and development
  • Disease processes research
  • Expression proteomics
  • Interaction proteomics and protein networks
  • Post-translational modifications
  • Responses to environment

Features

Collaboration with industry where the institute collaborated with Proteomics expertise (in the last 5 years) <10
% of TIME involved in technology/methods development/innovation/intellectual property related to Proteomics 20%

Track record

Key opinion leaders
  • Eduardo Chicano-Galvez, MS-Imaging Expert, Bioinformatics, Quantitative Proteomics.
Publications

DATA ANALYSIS for

  • Genomics
  • Proteomics
  • Metabolomics
  • Omics data integration/systems biology

DATA INTERPRETATION for

  • Genomics
  • Proteomics
  • Metabolomics
  • Omics data integration/systems biology

 STATISTICS

  • Molecular profiling (omics and others)

 BIOINFORMATICS

  • Genes and proteins annotation
  • Expression profiling with omics, microarrays and others (e.g. PCR) for RNAseq, microRNA, other RNA species and proteins
  • Methylation profiling with array-types
  • Genetic analysis for Structural variation detection (Genome, Exome)
  • Semantic analysis (“Bibliome analysis”, text mining)
  • Development of new algorithms, e.g. new decision algorithms, new sequence aligners for NGS data, etc.

OMICS INTEGRATION METHODS

  • Own scripts/software