The “Fundación para la Investigación del Hospital Clínico de la Comunidad Valenciana”-INCLIVA is a top 10 biomedical research institute in Spain. INCLIVA is included in the framework of centres of scientific excellence promoted by the Spanish Ministry of Economy and Competitiveness, and it has been accredited by the National Health Institute Carlos III as an Institute of Research in Health Sciences.
INCLIVA is the institution managing the research for Health of the University of Valencia (School of Medicine) and the University Clinic Hospital that include a Department providing healthcare to the 350.000 inhabitants with a EHR that virtually covers the whole population of the department. INCLIVA has participated in FP6, FP7 and H2020 research projects funded by the European Commission.
INCLIVA is organized around four priority areas of research:
- Oncology: INCLIVA is an international leader in the field of oncology and hematology, with eleven research groups and more than 125 researchers, coordinated by Dr. Andrés Cervantes. The main research lines focus on cancer cell biology, genetic analysis of tumors and development of precision medicine through experimental therapies. INCLIVA belongs to the WIN Consortium “Worldwide Innovative Networking (WIN) Consortium in personalized cancer medicine” and in 2015 the Oncology team had more than 215 clinical trials active.
- Cardiovascular diseases: eleven research groups and 120 researchers, coordinated by Dr. Francisco Javier Chorro. The main areas of research focus on experimental cardiac electrophysiology, cardiometabolic and renal risk, diagnosis and treatment of primary hyperlipidemia, diabetes and inflammation. Studies focus on the development of experimental therapies and early diagnosis combining genetic, epigenetic, metabolomics or image analysis techniques. In 2015 the cardiovascular diseases area had 47 clinical trials active.
- Healthy ageing: addresses aging at physical and neurological level, led by Dr. Jose Viña. The research focuses on the influence of oxidative stress and free radicals in aging and neurological deterioration, identification of biomarkers and genetic and epigenetic determinants and in the molecular study of the protective role of physical exercise. In this context it is worth to remark that INCLIVA is one of the founding members of the Spanish group for the study of centenarians.
- Reproductive medicine: INCLIVA is also a part of the Valencia Infertility Institute, IVI, coordinated by Dr. Carlos Simon. The research developed at IVI focuses on two lines of action. Firstly the study of biological functions in the human endometrium, the analysis and development of diagnostic techniques to determine the right time of endometrial reception using genomics. And a second focused on male infertility, particularly in the treatment of azoospermia and seminal breathing.