Our main interest is the understanding of mechanisms and cellular functions of RNA-binding proteins and their role in post-transcriptional regulatory networks that control gene expression.
Post-transcriptional regulation is highly versatile and adaptable in exploiting cellular time and space. RNA-binding proteins play a key role in the regulation of spatial and temporal changes in protein synthesis through control of transport, translation and decay of mRNA. Deregulation and failed coordination of these mechanisms contribute to the pathophysiological development and conditions.
For further information please see here: https://www.lih.lu/en/event/posttranscriptional-regulation-in-cellular-time-and-space/