EATRIS Guest Edits Cell & Gene Therapy Insights Special Issue on Expanding Cellular Immunotherapy

Published 24 March 2025

EATRIS has guest-edited the February edition of Cell & Gene Therapy Insights, titled “Expanding the range of cellular immunotherapy.” This special issue brings together leading experts to explore the latest advancements, challenges, and opportunities in broadening the scope and impact of cellular immunotherapies.

Cellular immunotherapy has revolutionised the treatment landscape for a growing number of diseases, from haematological malignancies to autoimmune conditions. However, to fully realise the potential of these therapies, it is critical to address key barriers such as accessibility, affordability, and applicability beyond current indications. 

In this special issue of Cell & Gene Therapy Insights, experts from academia, industry, and regulatory bodies provide insights into cutting-edge strategies for expanding the reach of cellular immunotherapies. Topics covered include novel cell engineering approaches, manufacturing innovations, regulatory considerations, and emerging therapeutic applications. 

A Foreword from EATRIS 

The foreword, co-authored by Anton Ussi (Operations & Finance Director, EATRIS), Toni Andreu (Scientific Director, EATRIS), Florence Bietrix (Deputy Director to the Executive Board, EATRIS), and David Morrow (Senior Scientific Programme Manager, EATRIS) highlights the importance of multidisciplinary collaboration in overcoming translational challenges and ensuring that innovative cell-based therapies reach the patients who need them most. 

Key Highlights from the Issue 

  • Innovations in CAR-T & TCR therapies – Exploring next-generation cellular therapies and their clinical potential. 
  • Expanding indications – Investigating applications beyond oncology, including autoimmune diseases and regenerative medicine. 
  • Manufacturing & scalability – Addressing challenges in production, standardisation, and global accessibility. 
  • Regulatory perspectives – Insights into streamlining approval pathways for emerging therapies. 

Driving Innovation in Advanced Therapies 

As part of our commitment to advancing translational research, EATRIS continues to support initiatives that bridge the gap between scientific discovery and patient impact. By guest-editing this issue, we contribute to the ongoing dialogue on making cellular immunotherapies more accessible and impactful.