The EATRIS-Plus project team has published a new peer-reviewed article in Phenomics that highlights one of the key achievements of the EATRIS-Plus project: the development of the Multi-Omics Toolbox (MOTBX). The article showcases how the consortium partners have advanced standardisation and quality assurance in clinical omics research, helping to bridge the gap between innovation and patient care.
Molecular profiling — using omics tools such as genomics, transcriptomics, proteomics and metabolomics — is unlocking new possibilities for truly personalised healthcare. By “zooming in” on the unique molecular makeup of each patient’s samples, researchers can tailor treatments to be more effective, with fewer side effects. But before these powerful technologies can become routine clinical tools, they must be built on a foundation of consistency and quality. That means every lab needs to follow shared protocols, use the same reference materials, and analyse data in a standardised way.
That’s where EATRIS comes in. As the European Infrastructure for Translational Medicine, we connect experts, technologies and quality-assurance resources across the continent. Through the Horizon 2020-funded EATRIS-Plus project, our member institutes have collaborated to:
- Standardise sample handling – From collection to storage, clear protocols ensure that biological samples yield trustworthy data.
- Harmonise data generation – Whether sequencing DNA, measuring proteins or profiling metabolites, shared benchmarks allow labs to produce directly comparable results.
- Integrate multi-omics datasets – Combining genomics, transcriptomics, proteomics and more offers a fuller view—our workflows ensure this integration is scientifically sound.
- Deliver practical tools – All resources, including guidelines, reference materials and software pipelines, are bundled in the Multi-Omics Toolbox—a one-stop shop for high-quality, reproducible omics research.
These achievements are showcased in a new peer-reviewed publication co-authored by members of the EATRIS community, now available in the journal Phenomics. The article outlines how infrastructure-supported collaboration is helping to overcome reproducibility challenges and establish robust standards for clinical omics research.
By promoting harmonised procedures and shared standards, EATRIS-Plus is helping to close the gap between innovative lab science and real-world patient impact. We invite researchers, clinicians and industry stakeholders to explore the Multi-Omics Toolbox and join us in shaping a future where every patient benefits from precise, molecularly informed healthcare.
