Master module X-omics and biomarkers

Course provider Radboud University
Duration 2 days/week for 4 consecutive weeks (01-10-2018 till 25-08-2019)
Location Radboud University (Nijmegen, the Netherlands)
Language English

Radboud University will be organising a master module on translational biomarkers based on X-omics approaches in October 2018. The module will be 2 days/week for 4 consecutive weeks and will be a combination of theoretical lectures, hands-on work on sample and data analysis, complemented with practical use cases.  The master course is also open for external PhD students.


Course Objectives

After completing of the course, students are able to

  1. Define the added value of molecular biomarkers in modern life sciences
  2. Explain the various steps in biomarker discovery  and development
  3. Define the strength and pitfalls in biomarker research
  4. Select the proper omics technology to address a given translational biomarker need
  5. Explain the analytical basis of next generation sequencing and mass spectrometry
  6. Perform basic analysis of next generation sequencing and mass spectrometry data
  7. Design a X-omics study to identify and validate translational biomarkers

Course Content

This course focusses on molecular biomarkers that drive personalized healthcare and the use of omics technologies for biomarker identification and validation.
Following the landmark first map of a human genome, the field of molecular life sciences has seen multiple major breakthroughs. Detailed insights in molecular pathways, mechanism-based personalized diagnostics and personalized therapies have changed the way we practice medicine. These are enabled by our better grasp of the molecular building blocks of life: genes and their transcription, protein function and their interaction, and the complex dynamic networks of metabolites. The fields studying these building blocks, i.e. genomics, proteomics and metabolomics (collectively called omics), have seen great technological advances in recent years, resulting in increased throughput, higher accuracy and lower costs of measurements. The huge molecular complexity of human systems cannot be addressed through any of these omics technologies alone. Exciting recent developments show that it has now become technologically feasible to approach molecular biology from different omics angles simultaneously, fueling the new approach of X-omics for biomarker research.


Preregistration is open from 01-04-2018 t/m 01-06-2018 and the course also welcomes external Phd students.

To find out more, please visit the dedicated webpage here

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