Hospital La Paz Institute for Health Research (IdiPAZ)

Address Paseo Castellana, 261
28046 ​ - ​ Madrid
Spain
Platforms ATMP & Biological, Biomarkers

“Hospital La Paz Institute for Health Research” (IdiPAZ) was created as a place for biomedical research, as a result of the relaionship that has been forged over the years between La Paz University Hospital (HULP), the Autonomous University of Madrid (UAM), and the Foundation for Biomedical Research of La Paz University Hospital (FIBHULP).

Since its formal constitution, on 15 December 2009, IdiPAZ it is an accredited institution by the Health Institute Carlos III (ISCIII), and re accredited on May 2015 for a 5 years period.

The scientific structure of IdiPAZ

53 research groups distributed according to three categories (established groups, consolidated groups and excellent groups), you can also belong to IdiPAZ as clinical associate. They focus their activities in six strategic areas:includes 48 research groups, adscribed by four categories (grupo constituido, consolidated group, excelent group, and associated clinician), that focus their activity on six strategic areas:

  • Neurosciences Area
  • Cardiovascular Area
  • Infectious diseases and immunity Area
  • Organ system Pathologies Area
  • Cancer and human Molecular Genetics Area
  • Surgery, transplant and health Technologies Area

IdiPAZ works to establish itself as a leader in translational biomedical research, national and international, to promote quality on the basic research, clinical research, epidemiological research, and health services research. In addition, our Institute aims to promote and develop programs and research projects or research training, with special attention to the training of professionals in scientific research methodology and the needs of the primary care setting.

Safeguarding the quality, ethics and ethical principles of research are cornerstones of the work IdiPAZ performs every day, in addition to promoting the efficient use of resources and infrastructures.

  • The ultimate goal of the Institute is to promote the translation of the results of the work of its researchers:
  • to society, transferring the knowledge generated from its activities in clinical practice
  • to the scientific world, by disseminating its activities across generated publications and scientific reports by the institute
  • to the economy by promoting innovation and the transfer of results

As an accredited Health Research Institute, IdiPAZ is involved in the “Spanish strategy for participation in scientific infrastructures and international organisations” promoted by the Spanish government in their document “Building 21st Century Science”. This strategy is based on the ESFRI (European Strategy Forum on Research Infrastructures) roadmap promoted by the European Union toact as an incubator and catalyst for initiatives of scientific facilities.

Institutes' Omics Technologies

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DATA ANALYSIS for

  • Genomics
  • Omics data integration/systems biology

DATA INTERPRETATION for

  • Genomics
  • Omics data integration/systems biology
  • Structural bioinformatics

DATA MANAGEMENT for

  • FAIR data

DATA SUBMISSION in to public database

STATISTICS

  • SPSS, R
  • Molecular profiling (omics and others)
  • Expertise in clinical design of experiments, clinical statistics
  • Metadata (patient/sample information)

BIOINFORMATICS

  • Genes and proteins annotation
  • Expression profiling with omics and microarrays for RNAseq, microRNA, other RNA species and proteins
  • Methylation profiling with NGS and array-types
  • Data integration (“Systems biology”)
  • Genetic analysis for Structural variation detection (Genome, Exome) and prediction of protein function from sequence information
  • Drug-target interaction analysis
  • Development of new algorithms, e.g. new decision algorithms, new sequence aligners for NGS data, etc.
  • Informatics methods to support clinical decisions (diagnostic, predictive tests)

OMICS INTEGRATION METHODS

  • Published tools